Tandem Photoredox Catalysis: Enabling Carbonylative Amidation of Aryl and Alkylhalides

José A. Forni Nenad Micic Dr. Timothy U. Connell Dr. Geethika Weragoda Dr. Anastasios Polyzos
Angew. Chem. 2020, 132,2-11. doi:
(Highlighted in Synfacts)


Photoexcited Pd(II) Auxiliaries Enable Light-Induced Control in C(sp3)–H Bond Functionalisation

Milena L. Czyz, Geethika K. Weragoda, Tyra H. Horngren, Timothy U. Connell, Daniel Gomez, Richard A. J. O’ Hair, Anastasios Polyzos
Chem. Sci., 2020, Advance Article. doi: 10.1039/C9SC05722F


The Tandem Photoredox Catalysis Mechanism of [Ir(ppy)2(dtb-bpy)]+ Enabling Access to Energy Demanding Organic Substrates

TU Connell, CL Fraser, ML Czyz, ZM Smith, DJ Hayne, EH Doeven, J Agugiaro, DJD Wilson, JL Adcock, AD Scully, DE Gómez, NW Barnett, A Polyzos, PS Francis
J. Am. Chem. Soc. 2019, 141, 44, 17646-17658. doi:


A Visible Light Photoredox Catalysed Radical Pictet-Spengler Reaction

Theerada Seehamongkol , Tyra H. Horngren , Mohammed A. M. Alhajji , Joshua Almond-Thynne , Milena L. Czyz , Anthony J. Barrett and Anastasios Polyzos
Aus. J. Chem. 2019, 72, 11 doi:


A Chemoselective and Scalable Transfer Hydrogenation of Aryl Imines by Rapid Continuous Flow Photoredox Catalysis

RL Pilkington, NP Rossouw, DJ van As, A Polyzos
Chimia. 2019, 73, 823.



Metallo-Cubosomes: Zinc-Functionalized Cubic Nanoparticles for Therapeutic Nucleotide Delivery

B Tajik-Ahmadabad, L Chollet, J White, F Separovic, A Polyzos
Mol. Pharm. 2019, 16, 978-986. doi: 10.1021/acs.molpharmaceut.8b00890



Radical Carbonylation Mediated by Continuous-Flow Visible-Light Photocatalysis: Access to 2, 3-Dihydrobenzofurans

N Micic, A Polyzos
Org. Lett. 2018, 20, 4663-4666. doi: 10.1021/acs.orglett.8b01971



Photocatalytic and Chemoselective Transfer Hydrogenation of Diarylimines in Batch and Continuous Flow

DJ van As, TU Connell, M Brzozowski, AD Scully, A Polyzos
Org. Lett. 2018, 20, 4905-908. doi: 10.1021/acs.orglett.7b03565



Regioselectivity of Aryl Radical Attack onto Isocyanates and Isothiocyanates

GK Weragoda, RL Pilkington, A Polyzos, AJ Richard
Org. Biomol. Chem. 2018,16, 9011-9020. doi: 10.1039/C8OB02209G



Bidirectional Synthesis of Di-tert-butyl (2S,6S,8S)- and (2R,6R,8R)-1,7-Diazaspiro[5.5]undecane-2,8-dicarboxylate and Related Spirodiamines

Joshua Almond-Thynne, Jiaxu Han, Andrew J. P. White, Anastasios Polyzos, Philip J. Parsons, Anthony G. M. Barrett
J. Org. Chem.2018, 83, 126783-6787 doi: 10.1021/acs.joc.8b00794


A Visible-light Photocatalytic Thiolation of Aryl, Heteroaryl and Vinyl Iodides 

ML Czyz, GK Weragoda, R Monaghan, TU Connell, M Brzozowski, AD Scully, J Burton, DW Lupton, A Polyzos
Org. Biomol. Chem. 2018,16, 1543-1551. doi: 10.1039/C8OB00238J



Auxiliary‐Directed C(sp3)−H Arylation by Synergistic Photoredox and Palladium Catalysis

Milena L Czyz, David W Lupton, Anastasios Polyzos
Chem. Eur. J. 2017, 23, 14450-14453. doi:10.1002/chem.201704045 



Synthesis and Reactions of Benzannulated Spiroaminals:

Joshua Almond-Thynne, Andrew J. P. White, Anastasios Polyzos, Henry S. Rzepa,
Philip J. Parsons and Anthony G. M. Barrett
ACS Omega 2017, 2, 3241−3249 doi: 10.1021/acsomega.7b00482


Luminescence of a Transition Metal Complex Inside a Metamaterial Nanocavity

Timothy U Connell, Stuart K Earl, Charlene Ng, Ann Roberts, Timothy J Davis, Jonathan M White, Anastasios Polyzos, Daniel E Gómez
Small. 2017, 13, 1700692. doi: 10.1002/smll.201700692


Amphiphilic Lipopeptide Significantly Enhances Uptake of Charge-neutral Splice Switching Morpholino Oligonucleotide in Spinal Muscular Atrophy Patient-derived Fibroblasts

Behnoosh Tajik-Ahmadabad, Anastasios Polyzos, Frances Separovic, Fazel Shabanpoorc
Int. J. Pharm. 201, 532, doi:10.1016/j.ijpharm.2017.08.116



A QCM‐D and SAXS Study of the Interaction of Functionalised Lyotropic Liquid Crystalline Lipid Nanoparticles with siRNA

Behnoosh Tajik‐Ahmadabad, Adam Mechler, Benjamin W Muir, Keith McLean, Tracey M Hinton, Frances Separovic, Anastasios Polyzos
Chem. Bio.Chem. 2017, 18, 921-930. doi: 10.1002/cbic.201600613



Rapid Microwave-Assisted Synthesis of N-Aryl 1, 2, 3, 4-Tetrahydroisoquinolines

José Augusto Forni, Martin Brzozowski, John Tsanaktsidis, G Paul Savage, Anastasios Polyzos
Aust. J. Chem. 2015, 68, 1890-1893. doi:10.1071/CH15490



Scalable Simultaneous Activation and Separation of Metal–organic Frameworks

Marta Rubio-Martinez, Thomas Leong, Pablo Juliano, Trevor D Hadley, Michael P Batten, Anastasios Polyzos, Kok-Seng Lim, Matthew R Hill
RSC Adv., 2016, 6, 5523-5527. doi: 10.1039/C5RA24994E



Triphenylphosphine-grafted, RAFT-synthesised, Porous Monoliths as Catalysts for Michael Addition in Flow Synthesis

Kristine J Barlow, Victor Bernabeu, Xiaojuan Hao, Timothy C Hughes, Oliver E Hutt, Anastasios Polyzos, Kathleen A Turner, Graeme Moad
React. Funct. Polym. 2015, 96, 89-96. doi: 10.1016/j.reactfunctpolym.2015.09.008



Continuous Flow Production of Metal-organic Frameworks

Michael P Batten, Marta Rubio-Martinez, Trevor Hadley, Keri-Constanti Carey, Kok-Seng Lim, Anastasios Polyzos, Matthew R Hill
Curr. Opin. Chem. Eng. 2015, 8, 55-59. doi: 10.1016/j.coche.2015.02.001



Continuous Flow Synthesis of a Carbon-based Molecular Cage Macrocycle via a Three-fold Homocoupling Reaction

Melanie Kitchin, Kristina Konstas, Christopher J Sumby, Milena L Czyz, Peter Valente, Matthew R Hill, Anastasios Polyzos, Christian J Doonan
Chem. Commun., 2015, 51, 14231-14234. doi: 10.1039/C5CC05181A



The Direct α-C (sp 3)–H Functionalisation of N-aryl Tetrahydroisoquinolines via an Iron-catalysed Aerobic Nitro-Mannich Reaction and Continuous Flow Processing

Martin Brzozowski, Jose A Forni, G Paul Savage, Anastasios Polyzos
Chem. Commun., 2015, 51, 334-337. doi: 10.1039/C4CC07913B


Flow Chemistry: Intelligent Processing of Gas–liquid Transformations Using a Tube-in-tube Reactor

Martin Brzozowski, Matthew O’Brien, Steven V Ley, Anastasios Polyzos
Acc. Chem. Res. 2015, 48, 349-362. doi: 10.1021/ar500359m



Book Chapters

OʼBrien, A. Polyzos, A., Science of Synthesis: Flow Chemistry in Organic Synthesis, (20181, 243. DOI: 10.1055/sos-SD-228-00173.


Rubio-Martinez, M. P. Batten, A. Polyzos, K.-C. Carey, J. I. Mardel, K.-S. Lim, M. R, Hill, Production of Metal Organic Frameworks (2015), AU 2015203627 B1 20151210.

G. Hartley, A. Polyzos, Liquid crystal contrast agents. From PCT Int. Appl. (2009) WO 2010060131 A1.