Publications

Reductive Activation and Hydrofunctionalization of Olefins by Multiphoton Tandem Photoredox Catalysis

Milena L. Czyz, Mitchell S. Taylor, Tyra H. Horngren, Anastasios Polyzos

ACS Catal. 2021, 11, XXX, 5472–5480 doi: https://doi.org/10.1021/acscatal.1c01000

 

 

Enone-Promoted Decarboxylation of Trans-4-hydroxy-l-proline in Flow: A Side-by-Side Comparison to Batch

Rowan L. Pilkington, Madeleine A. Dallaston, Paul G. Savage, Craig M. Williams and Anastasios Polyzos

React. Chem. Eng., 2021, Advance Article doi: https://doi.org/10.1039/D0RE00442A

 

A Two-Step Catalytic Cycle for the Acceptorless Dehydrogenation of Ethane by Group 10 Metal Complexes: Role of the Metal in Reactivity and Selectivity

Kevin Parker, Geethika K. Weragoda, Allan J. Canty, Anastasios Polyzos, Victor Ryzhov, and Richard A. J. O’Hair

Organometallics 2020, 39, 22, 4027–4036 doi: https://doi.org/10.1021/acs.organomet.0c00598

 

Gas‐Phase Models for the Nickel‐ and Palladium‐Catalyzed Deoxygenation of Fatty Acids

Kevin Parker, Dr. Geethika K. Weragoda, Victoria Pho, Prof. Allan J. Canty, Dr. Anastasios Polyzos, Prof. Richard A. J. O’Hair, Prof. Victor Ryzhov

ChemCatChem 2020, 12, 5476. doi: https://doi.org/10.1002/cctc.202000908

 

Tandem Photoredox Catalysis: Enabling Carbonylative Amidation of Aryl and Alkylhalides

José A. Forni, Nenad Micic, Dr. Timothy U. Connell, Dr. Geethika Weragoda, Dr. Anastasios Polyzos

Angew. Chem. 2020, 132,2-11. doi: https://doi.org/10.1002/ange.202006720

(Highlighted in Synfacts)

 

Photoexcited Pd(II) Auxiliaries Enable Light-Induced Control in C(sp³)–H Bond Functionalisation

Milena L. Czyz, Geethika K. Weragoda, Tyra H. Horngren, Timothy U. Connell, Daniel Gomez, Richard A. J. O’ Hair, Anastasios Polyzos

Chem. Sci., 2020, Advance Article. doi: 10.1039/C9SC05722F

 

The Tandem Photoredox Catalysis Mechanism of [Ir(ppy)₂(dtb-bpy)]⁺ Enabling Access to Energy Demanding Organic Substrates

TU Connell, CL Fraser, ML Czyz, ZM Smith, DJ Hayne, EH Doeven, J Agugiaro, DJD Wilson, JL Adcock, AD Scully, DE Gómez, NW Barnett, A Polyzos, PS Francis

J. Am. Chem. Soc. 2019, 141, 44, 17646-17658. doi: https://doi.org/10.1021/jacs.9b07370

 

A Visible Light Photoredox Catalysed Radical Pictet-Spengler Reaction

Theerada Seehamongkol , Tyra H. Horngren , Mohammed A. M. Alhajji , Joshua Almond-Thynne , Milena L. Czyz , Anthony J. Barrett and Anastasios Polyzos

Aus. J. Chem. 2019, 72, 11 doi:  https://doi.org/10.1071/CH19423

 

A Chemoselective and Scalable Transfer Hydrogenation of Aryl Imines by Rapid Continuous Flow Photoredox Catalysis

RL Pilkington, NP Rossouw, DJ van As, A Polyzos

Chimia. 2019, 73, 823. https://chimia.ch/component/content/article/2086

 

 

Metallo-Cubosomes: Zinc-Functionalized Cubic Nanoparticles for Therapeutic Nucleotide Delivery

B Tajik-Ahmadabad, L Chollet, J White, F Separovic, A Polyzos

Mol. Pharm. 2019, 16, 978-986. doi: 10.1021/acs.molpharmaceut.8b00890

 

 

Radical Carbonylation Mediated by Continuous-Flow Visible-Light Photocatalysis: Access to 2, 3-Dihydrobenzofurans

N Micic, A Polyzos

Org. Lett. 2018, 20, 4663-4666. doi: 10.1021/acs.orglett.8b01971

 

 

Photocatalytic and Chemoselective Transfer Hydrogenation of Diarylimines in Batch and Continuous Flow

DJ van As, TU Connell, M Brzozowski, AD Scully, A Polyzos

Org. Lett. 2018, 20, 4905-908. doi: 10.1021/acs.orglett.7b03565

 

 

Regioselectivity of Aryl Radical Attack onto Isocyanates and Isothiocyanates

GK Weragoda, RL Pilkington, A Polyzos, AJ Richard

Org. Biomol. Chem. 2018,16, 9011-9020. doi: 10.1039/C8OB02209G

 

 

Bidirectional Synthesis of Di-tert-butyl (2S,6S,8S)- and (2R,6R,8R)-1,7-Diazaspiro[5.5]undecane-2,8-dicarboxylate and Related Spirodiamines

Joshua Almond-Thynne, Jiaxu Han, Andrew J. P. White, Anastasios Polyzos, Philip J. Parsons, Anthony G. M. Barrett

J. Org. Chem.2018, 83, 126783-6787 doi: 10.1021/acs.joc.8b00794

 

A Visible-light Photocatalytic Thiolation of Aryl, Heteroaryl and Vinyl Iodides 

ML Czyz, GK Weragoda, R Monaghan, TU Connell, M Brzozowski, AD Scully, J Burton, DW Lupton, A Polyzos

Org. Biomol. Chem. 2018,16, 1543-1551. doi: 10.1039/C8OB00238J

 

 

Auxiliary‐Directed C(sp³)−H Arylation by Synergistic Photoredox and Palladium Catalysis

Milena L Czyz, David W Lupton, Anastasios Polyzos

Chem. Eur. J. 2017, 23, 14450-14453. doi:10.1002/chem.201704045 

 

 

Synthesis and Reactions of Benzannulated Spiroaminals:
Tetrahydrospirobiquinolines

Joshua Almond-Thynne, Andrew J. P. White, Anastasios Polyzos, Henry S. Rzepa,
Philip J. Parsons and Anthony G. M. Barrett

ACS Omega 2017, 2, 3241−3249 doi: 10.1021/acsomega.7b00482

 

Luminescence of a Transition Metal Complex Inside a Metamaterial Nanocavity

Timothy U Connell, Stuart K Earl, Charlene Ng, Ann Roberts, Timothy J Davis, Jonathan M White, Anastasios Polyzos, Daniel E Gómez

Small. 2017, 13, 1700692. doi: 10.1002/smll.201700692

 

Amphiphilic Lipopeptide Significantly Enhances Uptake of Charge-neutral Splice Switching Morpholino Oligonucleotide in Spinal Muscular Atrophy Patient-derived Fibroblasts

Behnoosh Tajik-Ahmadabad, Anastasios Polyzos, Frances Separovic, Fazel Shabanpoorc

Int. J. Pharm. 201, 532, doi:10.1016/j.ijpharm.2017.08.116

 

 

A QCM‐D and SAXS Study of the Interaction of Functionalised Lyotropic Liquid Crystalline Lipid Nanoparticles with siRNA

Behnoosh Tajik‐Ahmadabad, Adam Mechler, Benjamin W Muir, Keith McLean, Tracey M Hinton, Frances Separovic, Anastasios Polyzos

Chem. Bio.Chem. 2017, 18, 921-930. doi: 10.1002/cbic.201600613

 

 

Rapid Microwave-Assisted Synthesis of N-Aryl 1, 2, 3, 4-Tetrahydroisoquinolines

José Augusto Forni, Martin Brzozowski, John Tsanaktsidis, G Paul Savage, Anastasios Polyzos

Aust. J. Chem. 2015, 68, 1890-1893. doi:10.1071/CH15490

 

 

Scalable Simultaneous Activation and Separation of Metal–organic Frameworks

Marta Rubio-Martinez, Thomas Leong, Pablo Juliano, Trevor D Hadley, Michael P Batten, Anastasios Polyzos, Kok-Seng Lim, Matthew R Hill

RSC Adv., 2016, 6, 5523-5527. doi: 10.1039/C5RA24994E

 

 

Triphenylphosphine-grafted, RAFT-synthesised, Porous Monoliths as Catalysts for Michael Addition in Flow Synthesis

Kristine J Barlow, Victor Bernabeu, Xiaojuan Hao, Timothy C Hughes, Oliver E Hutt, Anastasios Polyzos, Kathleen A Turner, Graeme Moad

React. Funct. Polym. 2015, 96, 89-96. doi: 10.1016/j.reactfunctpolym.2015.09.008

 

 

Continuous Flow Production of Metal-organic Frameworks

Michael P Batten, Marta Rubio-Martinez, Trevor Hadley, Keri-Constanti Carey, Kok-Seng Lim, Anastasios Polyzos, Matthew R Hill

Curr. Opin. Chem. Eng. 2015, 8, 55-59. doi: 10.1016/j.coche.2015.02.001

 

 

Continuous Flow Synthesis of a Carbon-based Molecular Cage Macrocycle via a Three-fold Homocoupling Reaction

Melanie Kitchin, Kristina Konstas, Christopher J Sumby, Milena L Czyz, Peter Valente, Matthew R Hill, Anastasios Polyzos, Christian J Doonan

Chem. Commun., 2015, 51, 14231-14234. doi: 10.1039/C5CC05181A

 

 

The Direct α-C (sp 3)–H Functionalisation of N-aryl Tetrahydroisoquinolines via an Iron-catalysed Aerobic Nitro-Mannich Reaction and Continuous Flow Processing

Martin Brzozowski, Jose A Forni, G Paul Savage, Anastasios Polyzos

Chem. Commun., 2015, 51, 334-337. doi: 10.1039/C4CC07913B

 

Flow Chemistry: Intelligent Processing of Gas–liquid Transformations Using a Tube-in-tube Reactor

Martin Brzozowski, Matthew O’Brien, Steven V Ley, Anastasios Polyzos

Acc. Chem. Res. 2015, 48, 349-362. doi: 10.1021/ar500359m

 

 

Book Chapters

OʼBrien, A. Polyzos, A., Science of Synthesis: Flow Chemistry in Organic Synthesis, (2018) 1, 243. DOI: 10.1055/sos-SD-228-00173.

Patents 

Rubio-Martinez, M. P. Batten, A. Polyzos, K.-C. Carey, J. I. Mardel, K.-S. Lim, M. R, Hill, Production of Metal Organic Frameworks (2015), AU 2015203627 B1 20151210.

G. Hartley, A. Polyzos, Liquid crystal contrast agents. From PCT Int. Appl. (2009) WO 2010060131 A1.